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Interactive video lesson plan for: The Tiny Fish That's Changing Modern Medicine

Activity overview:

The little fish Danio rerio holds secrets to understanding how vertebrates develop, how diseases like cancer work, and how we might one day learn how to regenerate human heart tissue.

Learn More About How Animals Re-Grow Limbs: https://www.youtube.com/watch?v=QFa6jP6WgzM

Hosted by: Michael Aranda
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Sources:
General:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386812/
https://www.theguardian.com/science/2013/sep/15/zebrafish-human-genes-project
http://www2.nsysu.edu.tw/Marine-Med/teacher/paper/zebrafish%20model.pdf
http://www.nature.com/nature/journal/v496/n7446/full/nature12111.html

BRAF and Melanoma:
http://phys.org/news/2011-03-stripes-zebrafish-human-melanoma-reveals.html
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348545/
https://ghr.nlm.nih.gov/gene/BRAF
http://www.cancer.org/cancer/skincancer-melanoma/detailedguide/melanoma-skin-cancer-treating-targeted-therapy
http://www.ncbi.nlm.nih.gov/pubmed/12068308/
http://www.sciencemuseum.org.uk/whoami/findoutmore/yourbody/whatiscancer/whatcausescancer
http://www.ncbi.nlm.nih.gov/pubmed/15694309
http://www.nature.com/nature/journal/v471/n7339/edsumm/e110324-10.html
https://ghr.nlm.nih.gov/primer/therapy/procedures

Stem Cells:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775137/
http://www.eurekalert.org/pub_releases/2013-10/bch-fft102113.php
http://stemcells.nih.gov/info/scireport/pages/chapter5.aspx
https://inis.iaea.org/search/search.aspx?orig_q=RN:46088260
https://www.themmrf.org/multiple-myeloma-knowledge-center/myeloma-treatments-guide/stem-cell-transplants/engraftment-and-recovery/
http://www.ncbi.nlm.nih.gov/pubmed/20473159
http://ir.fatetherapeutics.com/releasedetail.cfm?releaseid=888242

Heart regeneration:
https://labs.cellbio.duke.edu/Poss/Poss%20Lab/Research.html
http://www.cell.com/cell-reports/abstract/S2211-1247(15)00854-2
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597874/
http://www.sciencedirect.com/science/article/pii/S1873506114000841
http://www.nature.com/nature/journal/v464/n7288/full/nature08899.html
http://www.heart.org/HEARTORG/Conditions/HeartAttack/AboutHeartAttacks/About-Heart-Attacks_UCM_002038_Article.jsp#.V8L4PJMrJPM

Image Sources:
https://commons.wikimedia.org/wiki/File:Zebrafisch.jpg
https://commons.wikimedia.org/wiki/File:F_de_Castelnau-poissons_-_Diversity_of_Fishes_(Composite_Image).jpg
https://commons.wikimedia.org/wiki/File:Zebrafish_Developmental_Stages.tiff
http://www.nature.com/articles/srep29490
https://en.wikipedia.org/wiki/Prostaglandin_E2#/media/File:Prostaglandin_E2.svg
https://commons.wikimedia.org/wiki/File:Myocardial_infarction_2015.jpg

Tagged under: SciShow,science,Hank,Green,education,learn,The Tiny Fish That' Changing Modern Medicine,michael aranda,zebrafish,Danio rerio,vertebrates,disease,treatments,regeneration,genomes,genetics,genes,proteins,disease-causing genes,BRAFV600E,transparent,crystal,duplicate genes,melanoma,cancer,model,mutation,SETDB1,stem cell transplants,prostaglandin E2,hematopoietic,blood,leukemia,immune system disorder,ProHema,regeneration human tissue,heart,cardio,cardiac

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