A discussion of the controversies surrounding the RE-LY and ROCKET-AF trials, which led to the initial FDA approvals of dabigatran (Pradaxa) and rivaroxaban (Xarelto) respectively.
Original RE-LY Trial: http://www.ncbi.nlm.nih.gov/pubmed/19717844
Original ROCKET-AF Trial: http://www.ncbi.nlm.nih.gov/pubmed/21830957
BMJ Criticisms of Dabigatran RE-LY:
BMJ Criticism of ROCKET-AF and Rivaroxaban:
Recent media coverage of dabigatran and RE-LY:
Recent media coverage of rivaroxaban and ROCKET-AF:
Tagged under: anticoagulation,anticoagulant, ifb,atrial fibrillation,xarelto,dabigatran,noac,doac,tsoac,rivaroxaban,pradaxa,eliquis,edoxaban,xa inhibitor,direct thrombin inhibitor,warfarin,coumadin
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