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Interactive video lesson plan for: On the hunt for rare cancer cells

Activity overview:

In the first part of this video, a particle covered with DNA strands that can bind to a protein found on cancer cells approaches a cell. Though the particle does not directly contact the cell, the DNA strands entangle the cell, as demonstrated when the particle is pulled away and the cell is pulled towards the particle.

In the second part, a particle covered with small molecules that target the same cancer protein does not achieve the same strong binding, even though it comes in direct contact with the cell.

Read more about this research at MIT News: http://web.mit.edu/newsoffice/2012/capturing-rare-cancer-cells-1112.html

Video by Wesley Wong, Harvard Medical School.

Tagged under: cancer,microfluidic devices,chemotherapy,mechanical engineering,health,health sciences,health technology,tumors,circulating tumor cells

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1. Students enter a simple code

2. You play the video

3. The students comment

4. You review and reflect

* Whiteboard required for teacher-paced activities

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